The OSTEOPATHIC Trial

The OSTEOPATHIC Trial was completed by the Osteopathic Research Center in 2011. The study assessed the efficacy of osteopathic manipulative treatment in 455 patients with chronic low back pain. Over a dozen publications have reported on the OSTEOPATHIC Trial. A partial list of accessible publications is provided below.

Licciardone JC, Gatchel RJ. Nonpharmacologic Therapies for Low Back Pain. Ann Intern Med. October 2017. Available here

Licciardone JC, Gatchel RJ, Aryal S. Targeting Patient Subgroups With Chronic Low Back Pain for Osteopathic Manipulative Treatment: Responder Analyses From a Randomized Controlled Trial. J Am Osteopath Assoc. March 2016. Available here  

Licciardone JC, Gatchel RJ, Aryal S. Recovery from Chronic Low Back Pain After Osteopathic Manipulative Treatment: A Randomized Controlled Trial. J Am Osteopath Assoc. March 2016. Available here    

Licciardone, C. John, Aryal, Subhash. Clinical response and relapse in patients with chronic low back painfollowing osteopathic manual treatment: Results from the OSTEOPATHIC Trial. Man Ther. December 2014. Available here 

Licciardone, C. John, Kearns, M Cathleen, Crow, W. Thomas. Changes in biomechanical dysfunction and low back pain reduction with osteopathic manual treatment: Results from the OSTEOPATHIC Trial. Man Ther. August 2014. Available here 

Licciardone, C. John. Short-term dosing of manual therapies for chronic low back pain. The Spine J. June 2014. Available  here 

Licciardone, C. John, Kearns, M Cathleen, Minotti, E. Dennis. Outcomes of osteopathic manual treatment for chronic low back pain according to baseline pain severity: Results from the OSTEOPATHIC Trial. Man Ther. December 2013. Available here

Licciardone, C. John. Kearns, M Cathleen, Hodge, M. Lisa, Minotti, E. Dennis. Osteopathic manual treatment in patients with diabetes mellitus and comorbid chronic low back pain: Subgroup results from the OSTEOPATHIC Trial. J Am Osteopath Assoc. January 2013. Available here 

Licciardone, C. John, Minotti, E. Dennis, Gatchel, J. Robert, Kearns, M Cathleen, Singh, P. Karen. Osteopathic manual treatment and ultrasound therapy for chronic low back pain: A randomized control trial. Ann Fam Med. March 2013. Available here  

Licciardone, C. John, Gatchel, J. Robert, Kearns, M Cathleen, Minotti, E. Dennis. Depression, somatization and somatic dysfunction in patients with nonspecific chronic low back pain: Results from the OSTEOPATHIC Trial. J Am Osteopath Assoc. December 2012. Available here  

Licciardone, C. John, Kearns, M Cathleen, Hodge, M. Lisa, Bergamini. V.W. Michael. Associations of cytokine concentrations with key osteopathic lesions and clinical outcomes in patients with nonspecific chronic low back pain: Results from the OSTEOPATHIC Trial. J Am Osteopath Assoc. September 2012. Available here 

Licciardone, C. John, Kearns, M Cathleen. Somatic dysfunction and its association with chronic low back pain, back-specific functioning, and general health: Results from the OSTEOPATHIC Trial. J Am Osteopath Assoc. July 2012. Available here 

Licciardone JC, King HH, Hensel KL, Williams DG. OSTEOPAThic Health outcomes In Chronic low back pain: The OSTEOPATHIC Trial. Osteopath Med Prim Care April 2008. Available here